Tipifarnib [192185-72-1]
T6271
Overview
- SupplierTargetMol Chemicals
- Product NameTipifarnib [192185-72-1]
- Delivery Days Customer4
- CAS Number192185-72-1
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTipifarnib
- Estimated Purity99.22%
- Molecular FormulaC27H22Cl2N4O
- Molecular Weight489.4
- Scientific DescriptionTipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.
- Shelf life instruction3 years
- SMILESCn1cncc1[C@@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1
- Storage Instruction-20°C
- UNSPSC12352200
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