Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TIRAP Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TIRAP Polyclonal Antibody at dilution 1:30
TIRAP Polyclonal Antibody
E-AB-17096
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTIRAP Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
- UNSPSC12352203