Bio-Connect

Tiratricol [51-24-1]

HY-B1201
MedChem Express
CAS Number51-24-1
Product group Chemicals
Estimated Purity99.60
Molecular Weight621.93
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tiratricol [51-24-1]
  • Delivery Days Customer
    10
  • CAS Number
    51-24-1
  • Category Supplier
    CHEMICAL,general_chemicals_reagents
  • Certification
    Research Use Only
  • Estimated Purity
    99.60
  • Molecular Formula
    C14H9I3O4
  • Molecular Weight
    621.93
  • Scientific Description
    Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC50s of 20 microM and 32 microM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus). It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication.[2].
  • SMILES
    O=C(O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1
  • Storage Instruction
    -20°C, 3 years (Powder)
  • UNSPSC
    12352005