Tivozanib

MedChem Express

Tivozanib [475108-18-0]

10

475108-18-0

99.60

C22H19ClN4O5

454.86

Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy [1] .

O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4

-20°C,2°C to 8°C

12352200