Tivozanib (hydrate) [682745-40-0]
HY-112467
CAS Number682745-40-0
Product group Chemicals
Estimated Purity99.0
Molecular Weight472.88
Overview
- SupplierMedChem Express
- Product NameTivozanib (hydrate) [682745-40-0]
- Delivery Days Customer5
- CAS Number682745-40-0
- CertificationResearch Use Only
- Estimated Purity99.0
- Molecular FormulaC22H21ClN4O6
- Molecular Weight472.88
- Scientific DescriptionTivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy[1].
- SMILESO=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4.O
- Storage Instruction-20°C
- UNSPSC12352200
