Tivumecirnon [2174938-78-2]

MedChem Express

Tivumecirnon [2174938-78-2]

5

2174938-78-2

Research Use Only

99.85

C24H27Cl2F3N6O

543.41

Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, CCL17 and CCL22, thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity[1][2][3][4].

C[C@H](C1=C(C=C(C=C1)Cl)Cl)N2C3=NC(N4CC([C@H]5CCCN(C5)CCO)C4)=CN=C3C(C(F)(F)F)=N2

-20°C,2°C to 8°C

12352200