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Tizanidine-d4 (hydrochloride) [1188263-51-5]

Name: Tizanidine-d4 (hydrochloride) [1188263-51-5]
SKU: HY-B0194AS_M09
Availability: BackOrder

HY-B0194AS

CAS Number1188263-51-5

Product group Chemicals

Molecular Weight294.20

Overview

Supplier
MedChem Express
Product Name
Tizanidine-d4 (hydrochloride) [1188263-51-5]
Delivery Days Customer
10
CAS Number
1188263-51-5
Certification
Research Use Only
Molecular Formula
C9H5D4Cl2N5S
Molecular Weight
294.20
Scientific Description
Tizanidine-d4 hydrochloride is deuterium labeled Tizanidine hydrochloride (HY-B0194A). Tizanidine hydrochloride, a skeletal muscle relaxant, is an orally effective central alpha2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine hydrochloride primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine hydrochloride has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine hydrochloride can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/beta-catenin signaling pathways. Tizanidine hydrochloride can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI).
SMILES
ClC1=C(C2=NSN=C2C=C1)NC3=NC([2H])([2H])C([2H])([2H])N3.Cl
UNSPSC
12352200