Tizoxanide

MedChem Express

Tizoxanide [173903-47-4]

10

173903-47-4

Research Use Only

99.09

C10H7N3O4S

265.25

Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC 50 of 0.46microM and 0.15 microM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-kappaB and the MAPK signaling pathways in LPS-treated macrophage cells [1] [3] [4] [5] .

O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O

-20°C,2°C to 8°C

12352200