Tizoxanide (Standard)

MedChem Express

Tizoxanide (Standard) [173903-47-4]

5

Research Use Only

Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC 50 of 0.46microM and 0.15 microM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-kappaB and the MAPK signaling pathways in LPS-treated macrophage cells [1] [3] [4] [5] .

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