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TL02-59 (dihydrochloride) [2415263-06-6]

HY-112852A
MedChem Express
CAS Number2415263-06-6
Product group Chemicals
Molecular Weight682.56
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TL02-59 (dihydrochloride) [2415263-06-6]
  • Delivery Days Customer
    10
  • CAS Number
    2415263-06-6
  • Certification
    Research Use Only
  • Molecular Formula
    C32H36Cl2F3N5O4
  • Molecular Weight
    682.56
  • Scientific Description
    TL02-59 dihydrochloride is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. TL02-59 dihydrochloride inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 dihydrochloride potently suppresses acute myelogenous leukemia (AML) cell growth[1].
  • SMILES
    O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(OC4=C5C=C(OC)C(OC)=CC5=NC=N4)=C3.Cl.Cl
  • UNSPSC
    12352200