TL12-186 [2250025-88-6]
T34888
CAS Number2250025-88-6
Product group Chemicals
Estimated Purity98.20%
Molecular Weight931.46
Overview
- SupplierTargetMol Chemicals
- Product NameTL12-186 [2250025-88-6]
- Delivery Days Customer16
- CAS Number2250025-88-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTL12-186
- Estimated Purity98.20%
- Molecular FormulaC44H51ClN10O9S
- Molecular Weight931.46
- Scientific DescriptionTL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 inhibits CDK2/cyclin A and CDK9/cyclin T1 with IC50s of 73 and 55 nM, respectively.
- Shelf life instruction3 years
- SMILESO=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCC(=O)NCCOCCOCCN4CCN(C5=CC=C(C=C5)NC6=NC=C(Cl)C(=N6)NC=7C=CC=CC7S(=O)(=O)C(C)C)CC4)C3C2=O)CC1
- Storage Instruction-20°C
- UNSPSC12352200
