TL1A/TNFSF15, Mouse (HEK293, Fc)

MedChem Express

TL1A/TNFSF15, Mouse (HEK293, Fc)

10

Research Use Only

95.0

Tnfsf15

tumor necrosis factor (ligand) superfamily, member 15

Tl1, Tl1a, Tnlg1b, Vegi, tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15), tumor necrosis factor ligand 1b, vascular endothelial cell growth inhibitor, vascular endothelial growth inhibitor

Tumor necrosis factor ligand superfamily member 15

The TL1A protein (VEGI protein), belongs to the tumor necrosis factor (TNF) family and is a receptor for TNFRSF25 and TNFRSF6B. TL1A is involved in the activation of NF-kappaB and C-Jun pathways, which can be used as a regulator of mucosal immunity and participate in the immune pathway of inflammatory bowel disease (IBD) pathogenesis[1][2]. TL1A originates from endothelial cells and inhibits the proliferation of breast cancer, epithelial and myeloid tumor cells[3]. The mouse TL1A protein has a transmembrane domain (40-60 a.a.) that can be cleaved into membrane-type and soluble peptide fragments. TL1A/TNFSF15 Protein, Mouse (HEK293, Fc) is the extracullar part of TL1A protein (A61-L252), produced in HEK293 cells with N-terminal hFc-tag.

-20°C

41116100