TL1A/TNFSF15, Rat (HEK293, Fc)

MedChem Express

TL1A/TNFSF15, Rat (HEK293, Fc)

10

Research Use Only

96.60

Tnfsf15

TNF superfamily member 15

TNF ligand-related molecule 1; Tnlg1b; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand 1b; tumor necrosis factor ligand superfamily member 15; tumor necrosis factor superfamily member 15; vascular endothelial cell growth inhibitor

Tumor necrosis factor ligand superfamily member 15

The TL1A protein (VEGI protein), belongs to the tumor necrosis factor (TNF) family and is a receptor for TNFRSF25 and TNFRSF6B. TL1A is involved in the activation of NF-kappaB and C-Jun pathways, which can be used as a regulator of mucosal immunity and participate in the immune pathway of inflammatory bowel disease (IBD) pathogenesis[1][2]. TL1A originates from endothelial cells and inhibits the proliferation of breast cancer, epithelial and myeloid tumor cells[3]. The rat TL1A protein has a transmembrane domain (40-60 a.a.) that can be cleaved into membrane-type and soluble peptide fragments. TL1A/TNFSF15 Protein, Rat (HEK293, Fc) is the extracullar part of TL1A protein (D94-I252), produced in HEK293 cells with N-terminal hFc-tag.

-20°C

41116100