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TLK1 antibody [N2C2], Internal

GTX102891
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetTLK1
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Overview

  • Supplier
    GeneTex
  • Product Name
    TLK1 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.9 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9874
  • Target name
    TLK1
  • Target description
    tousled like kinase 1
  • Target synonyms
    PKU-beta, serine/threonine-protein kinase tousled-like 1, SNARE protein kinase SNAK, serine threonine protein kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UKI8
  • Protein Name
    Serine/threonine-protein kinase tousled-like 1
  • Scientific Description
    The Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Liaw GJ, Chiang CS. Inactive Tlk associating with Tak1 increases p38 MAPK activity to prolong the G2 phase. Sci Rep. 2019,9(1):1885. doi: 10.1038/s41598-018-36137-1
    Read this paper
  • Singh V, Connelly ZM, Shen X, et al. Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity. Cell Cycle. 2017,16(10):915-926. doi: 10.1080/15384101.2017.1314421
    Read this paper
  • Awate S, De Benedetti A. TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint. BMC Mol Biol. 2016,17:3. doi: 10.1186/s12867-016-0056-x
    Read this paper