TLR7 agonist 20 [3029695-00-6]

TargetMol Chemicals

TLR7 agonist 20 [3029695-00-6]

9

Research Use Only

C22H24N4O

360.45

TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 microM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.

OCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC

-20°C

12352200