TLR7/8 agonist 6 [2115702-83-3]

MedChem Express

TLR7/8 agonist 6 [2115702-83-3]

10

2115702-83-3

Research Use Only

C24H27N5O2

417.50

TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 microM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for researching infectious disease, cancer, and autoimmune disorders[1].

CCCCC1=NC2=C(N=C3C=C(C=CC3=C2N1CC4=CC=C(CN)C=C4)C(OC)=O)N

12131703