TM5441

MedChem Express

TM5441

10

1190221-43-2

Research Use Only

99.08

C21H17ClN2O6

428.82

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 microM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nomega-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence[1][2].

ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1

-20°C,2°C to 8°C

12352200