TM5441 sodium [2319722-53-5]

TargetMol Chemicals

TM5441 sodium [2319722-53-5]

16

Chemical

Research Use Only

TM5441 sodium

C21H16ClN2NaO6

450.8

TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 microM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nomega-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].

3 years

N(C(COCC(NC1=C(C(O)=O)C=C(Cl)C=C1)=O)=O)C=2C=C(C=CC2)C=3C=COC3.[Na]

-20°C

12352200