TMC647055 Choline Hydroxide Salt

TargetMol Chemicals

TMC647055 Choline Hydroxide Salt

9

Chemical

Research Use Only

TMC647055 Choline Hydroxide Salt

99.44%

C37H53N5O8S

727.91

TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)>20 microM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro biochemical, kinetic, and virological profile that is currently undergoing clinical evaluation.

3 years

CN(CCOCCN1C)C(C2=CC3=C(C=CC(OC)=C3)C4=C(C5CCCCC5)C(C=CC(/C(O)=N/S1(=O)=O)=C6)=C6N4C2)=O.OCC[N+](C)(C)C.[OH-]

-20°C

12352200