WB analysis of PANC1 cells using GTX47035 TMEM2 antibody at 0.2-1microg/ml.
WB analysis of PANC1 cells using GTX47035 TMEM2 antibody at 0.2-1microg/ml.
TMEM2 antibody, Internal
GTX47035
Overview
- SupplierGeneTex
- Product NameTMEM2 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID23670
- Target nameCEMIP2
- Target descriptioncell migration inducing hyaluronidase 2
- Target synonymscell surface hyaluronidase; TMEM2; transmembrane protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9UHN6
- Protein NameCell surface hyaluronidase
- Scientific DescriptionThis gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203