TMP778

Biorbyt

TMP778

10

Research Use Only

TMP778 (TMP-778) is a potent, selective RORgammat inhibitor with IC50 of 7 nM in FRET assays and 63 nM in IL-17 promoter assays, with no inverse agonist activity.

C(N[C@@H](C1=CC=C(C)C=C1C)C1=CC=CC=C1)(=O)CC1=CC=C2OC(C(C3=C(C)ON=C3C)O)=CC2=C1

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