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TMPRSS11D antibody

Research Use Only
GTX117370
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTMPRSS11D
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    TMPRSS11D antibody
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.62 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9407
  • Target name
    TMPRSS11D
  • Target description
    transmembrane serine protease 11D
  • Target synonyms
    adrenal secretory serine protease; airway trypsin-like protease; ASP; HAT; transmembrane protease serine 11D; transmembrane protease, serine 11D
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus. Sato K et al., 2021 Oct 13, J Virol
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  • Host serine proteases TMPRSS2 and TMPRSS11D mediate proteolytic activation and trypsin-independent infection in group A rotaviruses. Sasaki M et al., 2021 Mar 24, J Virol
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  • TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein. Kishimoto M et al., 2021 Feb 28, Viruses
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  • The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells. Yamaya M et al., 2015 Aug, Pulm Pharmacol Ther
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