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TMPRSS11D antibody

Name: TMPRSS11D antibody
SKU: GTX117370_G10
Availability: BackOrder

GTX117370

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetTMPRSS11D

Overview

Supplier
GeneTex
Product Name
TMPRSS11D antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.62 mg/ml
Conjugate
Unconjugated
Gene ID9407
Target name
TMPRSS11D
Target description
transmembrane serine protease 11D
Target synonyms
ASP, HAT, transmembrane protease serine 11D, adrenal secretory serine protease, airway trypsin-like protease, transmembrane protease, serine 11D
Host
Rabbit
Isotype
IgG
Protein IDO60235
Protein Name
Transmembrane protease serine 11D
Scientific Description
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Sato K, Hayashi H, Shimotai Y, et al. TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus. J Virol. 2021,95(21):e0129621. doi: 10.1128/JVI.01296-21
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Sasaki M, Itakura Y, Kishimoto M, et al. Host serine proteases TMPRSS2 and TMPRSS11D mediate proteolytic activation and trypsin-independent infection in group A rotaviruses. J Virol. 2021,95(11):pii: JVI.00398-21. doi: 10.1128/JVI.00398-21.
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Kishimoto M, Uemura K, Sanaki T, et al. TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein. Viruses. 2021,13(3). doi: 10.3390/v13030384
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Yamaya M, Shimotai Y, Hatachi Y, et al. The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells. Pulm Pharmacol Ther. 2015,33:66-74. doi: 10.1016/j.pupt.2015.07.001
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