TMPRSS2 ELISA Kit (Human)

Aviva Systems Biology

TMPRSS2 ELISA Kit (Human)

23

Quantitative Sandwich ELISA

ELISA

0.156-10ng/mL

< 0.056 ng/mL

Aviva Systems Biology TMPRSS2 ELISA Kit (Human) (OKDD00567) is based on standard sandwich enzyme-linked immuno-sorbent assay methodology. An antibody for TMPRSS2 has been pre-coated onto a 96-wellplate (12 x 8 Well Strips). Standards or test samples...

~4 Hours

Research Use Only

Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.

Human

41116100

Human