TMS1 antibody
GTX133581
Overview
- SupplierGeneTex
- Product NameTMS1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2.07 mg/ml
- ConjugateUnconjugated
- Gene ID29108
- Target namePYCARD
- Target descriptionPYD and CARD domain containing
- Target synonymsapoptosis-associated speck-like protein containing a CARD; ASC; CARD5; caspase recruitment domain-containing protein 5; target of methylation-induced silencing 1; TMS; TMS1; TMS-1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203