TNF-alpha-IN-11

TargetMol Chemicals

TNF-alpha-IN-11

999

Research Use Only

TNF-alfa-IN-11

C24H26N2O5

422.47

TNF-alpha-IN-11 (Compound 10) is a TNF-alpha inhibitor with a dissociation constant (K D) of 12.06 microM. It impedes TNF-alpha-induced caspase activation and the NF-kappaB signaling pathway by binding to TNF-alpha, suppressing the phosphorylation of IkappaBalpha and the nuclear migration of NF-kappaB p65. This compound is utilized in the study of TNF-alpha-mediated autoimmune diseases [1].

3 years

-20°C

51202000