Fig-1: Induction of TNF-alpha promoter activity by phorbol 12-myristate 13-acetate in TNF-alpha HEK293 cells.
Fig-1: Induction of TNF-alpha promoter activity by phorbol 12-myristate 13-acetate in TNF-alpha HEK293 cells.
TNF-alpha Luciferase Reporter-HEK293 Cell Line
RC1005
Product group (Cell) Culture
Overview
- SupplierBoster Bio
- Product NameTNF-alpha Luciferase Reporter-HEK293 Cell Line
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Scientific DescriptionThe TNF-alpha Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimers disease. The TNF-alpha induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207