TNF-alpha/TNFSF2, Canine

MedChem Express

TNF-alpha/TNFSF2, Canine

10

Research Use Only

96.10

TNF

tumor necrosis factor

TNFA, TNLG1F, cTNF, tumor necrosis factor, TNF-a, TNF-alpha, cachectin, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha, tumour necrosis factor

Tumor necrosis factor

Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Canine is a recombinant protein produced in E. coli.

-20°C

41116100