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TNF-alpha/TNFSF2, Rabbit

Name: TNF-alpha/TNFSF2, Rabbit
SKU: HY-P70800_M09
Availability: BackOrder

HY-P70800

Protein IDP04924

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
TNF-alpha/TNFSF2, Rabbit
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
98.0
Gene ID100009088
Target name
TNF
Target description
tumor necrosis factor
Target synonyms
cachectin; TNFA; TNF-a; TNF-alpha; TNFSF2; TNLG1F; tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2
Protein IDP04924
Protein Name
Tumor necrosis factor
Scientific Description
Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 protein, Rabbit is a recombinant protein consisting of 158 amino acids (V78-L235) and is produced in E. coli.
Storage Instruction
-20°C
UNSPSC
41116100