TNF-alpha/TNFSF2, Rhesus macaque

MedChem Express

TNF-alpha/TNFSF2, Rhesus macaque

10

Research Use Only

95.0

TNF

tumor necrosis factor

EGK_14705, TNF-ALPHA, TNLG1F, tumor necrosis factor, ATP-binding cassette, sub-family F (GCN20), member 1, TNF-a, cachectin, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, tumor necrosis factor ligand 1F, tumor necrosis factor ligand superfamily member 2

Tumor necrosis factor

Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Rhesus macaque is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.

-20°C

41116100