IHC-P analysis of human breast carcinoma using GTX81327 TNK1 antibody, Internal.
IHC-P analysis of human breast carcinoma using GTX81327 TNK1 antibody, Internal.
TNK1 antibody, Internal
GTX81327
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTNK1
Overview
- SupplierGeneTex
- Product NameTNK1 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8711
- Target nameTNK1
- Target descriptiontyrosine kinase non receptor 1
- Target synonymsCD38 negative kinase 1; KOS1; non-receptor tyrosine-protein kinase TNK1
- HostRabbit
- IsotypeIgG
- Protein IDQ13470
- Protein NameNon-receptor tyrosine-protein kinase TNK1
- Scientific DescriptionThe protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203