TNNT1 Polyclonal Antibody

Reddot Biotech

TNNT1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.32 mg/ml

Unconjugated

TNNT1

troponin T1, slow skeletal type

ANM; NEM5; slow skeletal muscle troponin T; STNT; TNT; TNTS; troponin T type 1 (skeletal, slow); troponin T, slow skeletal muscle; troponin-T1, skeletal, slow

Rabbit

IgG

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Human

-20°C

12352203