TO-PRO 1

MedChem Express

TO-PRO 1 [157199-59-2]

5

157199-59-2

Research Use Only

5 mM

96.0

C24H29I2N3S

645.38

TO-PRO 1 is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm). TO-PRO 1 can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. TO-PRO 1 is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. TO-PRO 1 can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. TO-PRO 1 can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies[1][2][3].

C[N+](CCC[N+]1=C2C=CC=CC2=C(/C=C3SC4=CC=CC=C4N\3C)C=C1)(C)C.[I-].[I-]

-20°C

41116134