Toceranib

MedChem Express

Toceranib [356068-94-5]

10

356068-94-5

Research Use Only

96.86

C22H25FN4O2

396.46

Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR , VEGFR , and Kit with K i s of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors [1] [2] .

O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C

-20°C,2°C to 8°C

12352200