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Toceranib (phosphate)

HY-10330A
MedChem Express
CAS Number874819-74-6
DownloadMSDS
Product group Chemicals
Estimated Purity98.54
Molecular Weight494.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Toceranib (phosphate) [874819-74-6]
  • Delivery Days Customer
    10
  • CAS Number
    874819-74-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.54
  • Molecular Formula
    C22H28FN4O6P
  • Molecular Weight
    494.45
  • Scientific Description
    Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR , VEGFR , and Kit with K i s of 5 and 6 nM for PDGFRbeta and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors [1] [2] .
  • SMILES
    O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C.O=P(O)(O)O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200