Bio-Connect

Tofacitinib Prodrug-1

HY-145829
MedChem Express
Molecular Weight759.21
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tofacitinib Prodrug-1
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C36H39ClN10O7
  • Molecular Weight
    759.21
  • Scientific Description
    Tofacitinib precursor-1 is an effective and oral active precursor to mitigate the systemic adverse effects of Tofacitinib. Tofacitinib precursor-1 can effectively attenuate the oxazolone-induced colitis in mice model with low toxicity. Tofacitinib precursor-1 is a potential drug candidate for the research of ulcerative colitis[1].
  • SMILES
    O=C(O)C1=CC(/N=N/C2=CC=C(COC(NCCCN(C)C(N3C=CC4=C(NC[C@@H]5CN(C(CC#N)=O)CC[C@H]5C)N=CN=C43)=O)=O)C(Cl)=C2)=CC=C1O
  • UNSPSC
    12131703