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Tofogliflozin (hydrate)

HY-13413
MedChem Express
CAS Number1201913-82-7
Product group Chemicals
Estimated Purity98.48
Molecular Weight404.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tofogliflozin (hydrate) [1201913-82-7]
  • Delivery Days Customer
    10
  • CAS Number
    1201913-82-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.48
  • Molecular Formula
    C22H28O7
  • Molecular Weight
    404.45
  • Scientific Description
    Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC 50 of 2.9 nM and K i values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2 [1] . Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells [2] .
  • SMILES
    O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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