Tolazamide [1156-19-0]

MedChem Express

Tolazamide [1156-19-0]

6

1156-19-0

Research Use Only

99.87

C14H21N3O3S

311.40

Tolazamide (U-17835) is an orally active sulfonylurea agent that inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (IC50 = 4.2 microM in HEK293 cells transfected with the human receptor). Tolazamide has anti-diabetic properties. Tolazamide can lower blood glucose in sulfonylurea class. Tolazamide decreases insulin dose while continuing to maintain adequate metabolic control. Tolazamide is able to improve or normalize hyperglycemia and HbA[1][2][3].

O=S(C1=CC=C(C)C=C1)(NC(NN2CCCCCC2)=O)=O

-20°C,2°C to 8°C

12352200