Bio-Connect

Tolcapone [134308-13-7]

HY-17406
MedChem Express
CAS Number134308-13-7
Product group Chemicals
Estimated Purity99.91
Molecular Weight273.24
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tolcapone [134308-13-7]
  • Delivery Days Customer
    10
  • CAS Number
    134308-13-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Hazard Information
    h410
  • Molecular Formula
    C14H11NO5
  • Molecular Weight
    273.24
  • Scientific Description
    Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits alpha-syn and Abeta42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma[1][2][3][4].
  • SMILES
    O=C(C1=CC(O)=C(O)C([N+]([O-])=O)=C1)C2=CC=C(C)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200