Bio-Connect

Tolinapant(ASTX660)

M9933
AbMole BioScience
CAS Number1799328-86-1
Product group Chemicals
Molecular Weight539.68
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Tolinapant(ASTX660)
  • Delivery Days Customer
    9
  • CAS Number
    1799328-86-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C30H42FN5O3
  • Molecular Weight
    539.68
  • Scientific Description
    ASTX660 is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP, it potently inhibited the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
  • SMILES
    CC1CN(CC(=O)N2CC(C)(C)C3=C2C=C(CC4=CC=C(F)C=C4)C(=N3)CO)C(CN1)CN5CCOCC5C
  • UNSPSC
    12352200

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