Tolinapant(ASTX660)
M9933
CAS Number1799328-86-1
Product group Chemicals
Molecular Weight539.68
Overview
- SupplierAbMole BioScience
- Product NameTolinapant(ASTX660)
- Delivery Days Customer9
- CAS Number1799328-86-1
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC30H42FN5O3
- Molecular Weight539.68
- Scientific DescriptionASTX660 is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP, it potently inhibited the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
- SMILESCC1CN(CC(=O)N2CC(C)(C)C3=C2C=C(CC4=CC=C(F)C=C4)C(=N3)CO)C(CN1)CN5CCOCC5C
- UNSPSC12352200