Tomivosertib HCl [1849590-02-8]

TargetMol Chemicals

Tomivosertib HCl [1849590-02-8]

86

Chemical

Research Use Only

Tomivosertib HCl

C17H21ClN6O2

376.845

Tomivosertib, also known as eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.

3 years

Cl.Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1

-20°C

12352200