
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846078ESR2HU at dilution of 1:100
TOPBP1 Antibody
CSB-PA846078ESR2HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTOPBP1
Overview
- SupplierCusabio
- Product NameTOPBP1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11073
- Target nameTOPBP1
- Target descriptionDNA topoisomerase II binding protein 1
- Target synonymsDNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; Dpb11; TOP2BP1; topoisomerase (DNA) II binding protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ92547
- Protein NameDNA topoisomerase 2-binding protein 1
- Scientific DescriptionRequired for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161