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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846078ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846078ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846078ESR2HU at dilution of 1:100

TOPBP1 Antibody

CSB-PA846078ESR2HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTOPBP1
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Overview

  • Supplier
    Cusabio
  • Product Name
    TOPBP1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID11073
  • Target name
    TOPBP1
  • Target description
    DNA topoisomerase II binding protein 1
  • Target synonyms
    DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; Dpb11; TOP2BP1; topoisomerase (DNA) II binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92547
  • Protein Name
    DNA topoisomerase 2-binding protein 1
  • Scientific Description
    Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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