Topiroxostat [577778-58-6]

MedChem Express

Topiroxostat [577778-58-6]

10

577778-58-6

Research Use Only

99.95

C13H8N6

248.24

Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment[1][2].

N#CC1=NC=CC(C2=NNC(C3=CC=NC=C3)=N2)=C1

-20°C,2°C to 8°C

12131703