Topo I/COX-2-IN-1

MedChem Express

Topo I/COX-2-IN-1 [3031418-84-2]

10

Research Use Only

C21H18ClFN2O3

400.83

Topo I/COX-2-IN-1 (1H-30) is a potential Topo I/COX-2 inhibitor. Topo I/COX-2-IN-1 inhibits COX-2 and Topo I with the IC50 value of 0.24 microM and 4.42 microM, respectively. Topo I/COX-2-IN-1 can induce apoptosis and inhibit migration of cancer cells, has anti-cancer activity[1].

CC1=C(C=CC=C1NC2=CC=C(C=C2C(NCC3=CC=C(C(O)=C3)O)=O)F)Cl

12131703