Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), CF740 conjugate, 0.1mg/mL

Biotium

Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), CF740 conjugate, 0.1mg/mL

16

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

TOP2A/1361

0.1 mg/ml

Other Conjugate

TOP2A

DNA topoisomerase II alpha

TOP2, TOP2alpha, TOPIIA, TP2A, DNA topoisomerase 2-alpha, DNA gyrase, DNA topoisomerase (ATP-hydrolyzing), DNA topoisomerase II, 170 kD, DNA topoisomerase II, alpha isozyme, topoisomerase (DNA) II alpha 170kDa

IgG2b

DNA topoisomerase 2-alpha

This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIalpha. It shows no cross-reaction with topoisomerase IIbeta or topoisomerase I. Topo IIalpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIalpha is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C,RT

41116100