Topoisomerase II inhibitor 6

MedChem Express

Topoisomerase II inhibitor 6 [2987586-62-7]

10

Research Use Only

C19H18N4O2

334.37

Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective inhibitor of topoisomerase II. Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 blocks the cell cycle of CCRF-CEM in the G2 phase and induces DNA DSB. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases[1].

O=C1C2=NC3=C(C(N2C4=C1C(NCCN(C)C)=CC=C4)=O)C=CC=C3

12131703