TORC1 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX129355
Overview
- SupplierGeneTex
- Product NameTORC1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.9 mg/ml
- ConjugateUnconjugated
- Gene ID23373
- Target nameCRTC1
- Target descriptionCREB regulated transcription coactivator 1
- Target synonymsCREB-regulated transcription coactivator 1; Mam-2; MAML2; Mastermind-like protein 2; MECT1; mucoepidermoid carcinoma translocated protein 1; TORC1; TORC-1; transducer of regulated cAMP response element-binding protein (CREB) 1; WAMTP1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 Ser-133 phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203