Torin 2

MedChem Express

Torin 2 [1223001-51-1]

10

1223001-51-1

Research Use Only

99.65

C24H15F3N4O

432.40

Torin 2 is an mTOR inhibitor with EC 50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC 50 : 200 nM). Torin 2 also inhibits DNA-PK with an IC 50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2 .

O=C1N(C2=C(C=C1)C=NC3=CC=C(C=C32)C4=CC=C(N=C4)N)C5=CC=CC(C(F)(F)F)=C5

-20°C,2°C to 8°C

12352200