TP-064 [2080306-20-1]

TargetMol Chemicals

TP-064 [2080306-20-1]

9

2080306-20-1

Chemical

Research Use Only

TP-064

99.07%

C28H34N4O2

458.6

TP-064 is a potent and selective PRMT4 inhibitor, featuring an IC50 < 10nM for methylation of H3 (1-25) and over 100-fold selectivity compared to other histone methyltransferases and non-epigenetic targets. It inhibits the methylation of MED12 in cells with an IC50 of 43 nM.

3 years

CNCCN1CCC(CC1)c1cc(CN(C)C(=O)c2cccc(Oc3ccccc3)c2)ccn1

-20°C

12352200