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TP0427736 [864374-00-5]

TP0427736 [864374-00-5]

Research Use Only
T24897
TargetMol Chemicals
CAS Number864374-00-5
DownloadMSDS
Product group Chemicals
Estimated Purity97.67%
Molecular Weight298.39
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TP0427736 [864374-00-5]
  • Delivery Days Customer
    4
  • CAS Number
    864374-00-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TP0427736
  • Estimated Purity
    97.67%
  • Molecular Formula
    C14H10N4S2
  • Molecular Weight
    298.39
  • Scientific Description
    TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-beta-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse hair follicles.
  • Shelf life instruction
    3 years
  • SMILES
    CC=1N=C(C2=C(NC=N2)C=3C=C4C(=CC3)N=CS4)SC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200