TPC2-A1-N [136186-07-7]

MedChem Express

TPC2-A1-N [136186-07-7]

5

136186-07-7

Research Use Only

99.88%

C17H9Cl2F3N2O2

401.17

TPC2-A1-N is a powerful and Ca2+-permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP. TPC2-A1-P reproducibly evokes significant Ca2+ responses from TPC2 (EC50=7.8 microM), and the effect can be blocked by several TPC blockers. TPC2-A1-N can be used to probe different functions of TPC2 channels in intact cells.

O=C(NC1=CC=C(C(F)(F)F)C=C1)/C(C#N)=C(C2=CC(Cl)=CC(Cl)=C2)\O

2°C to 8°C,-20°C,-80°C

12352200