TPC2-A1-N

MedChem Express

TPC2-A1-N [136186-07-7]

10

136186-07-7

Research Use Only

99.86

C17H9Cl2F3N2O2

401.17

TPC2-A1-N is a powerful and Ca 2+ -permeable agonist of? two pore?channel?2?(TPC2) , which plays its role by mimicking the physiological actions?of?NAADP. TPC2-A1-P reproducibly?evokes significant Ca 2+ responses from TPC2 ( EC 50 =7.8 microM ), and the effect can be blocked by several TPC blockers. TPC2-A1-N can be used to probe different functions of TPC2 channels in intact cells [1] [2] .

O=C(NC1=CC=C(C(F)(F)F)C=C1)/C(C#N)=C(C2=CC(Cl)=CC(Cl)=C2)\O

-20°C,2°C to 8°C

12352200